R-MDDMA

Overview

R-MDDMA, 4-methylenedioxymethamphetamine (MDMA) analogue, is a 5-HT2A / 5-HT2C receptor modulator. R-MDDMA shows antagonistic activity against 5-HT2A/5-HT2C with IC 50 values of 642 and 137 nM, and also shows partial agonist activity with EC 50 values of 24.5 and 14.4 nM, but does not activate 5-HT2B receptors. R-MDDMA promotes cortical neuron growth. R-MDDMA facilitates fear extinction learning and produces antidepressant-like effects in preclinical rodent models. R-MDDMA can be used for the researches of post-traumatic stress disorder and depression.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-186169
• CAS No.: 872679-98-6
• Molecular Formula: C13H18O2
• Molecular Weight: 206.28
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source