α-Synuclein aggregate binder 3 is a probe for α-synuclein aggregates. The K i value of α-Synuclein aggregate binder 3 for binding to sonicated α-synuclein fibrils is 0.8 nM. α-Synuclein aggregate binder 3 can be used for α-synuclein imaging, as well as for detecting disorders associated with α-synuclein aggregation , such as Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.
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