Blapsin B is a potent 14-3-3 inhibitor and a naturally occurring compound from Blaps japanensis . Blapsin B potently inhibits 14-3-3 protein-protein interactions (PPIs) with an IC 50 value of 10.0 μM in the ELISA assay and 2.5 μM in the FP assay, respectively. Blapsin B modulates signaling pathways involved in cell proliferation and transformation. Blapsin B can be used for cancer research.
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