Albaconol

Overview

Albaconol is a prenylresorcinol compound. Albaconol is isolated from the mushroom A. confluens . Albaconol inhibits NF-κB and DNA topoisomerase II , and induces Apoptosis . Albaconol inhibits IκB-α phosphorylation and p65 nuclear translocation, enhances SOCS1 expression, reduces the production of proinflammatory cytokines and NO , and suppresses the expression of iNOS , MHC-II and co-stimulatory molecules. Albaconol acts as a weak antagonist of hVR1 and rVR1 , with IC 50 values of 17 µM and 5.5 µM, respectively. Albaconol induces tracheal contraction and desensitization. Albaconol inhibits the growth of tumor cells. Albaconol can be used in pain-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > IKK | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > MHC | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-N20661
• CAS No.: 338405-64-4
• Molecular Formula: C22H34O3
• Molecular Weight: 346.50
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source