p53 Bipartite NLS

Overview

p53 Bipartite NLS is a bipartite nuclear localization signal derived from p53 . When p53 Bipartite NLS is fused to the N-terminus of p65 and the single-component nuclear localization signal of p65 itself is mutated, it alters the nuclear import pathway of p65. p53 Bipartite NLS renders p65 resistant to TTP ( HY-P60128 )-mediated inhibition of NF-κB transcriptional activity and nuclear import.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Others | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-P11947
• CAS No.: 254103-71-4
• Molecular Formula: C85H148N28O26
• Molecular Weight: 1978.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source