CPP-115 hydrochloride

Overview

CPP-115 hydrochloride is an orally active, selective GABA-AT inhibitor with a K i value of 9.7 μM. CPP-115 hydrochloride blocks GABA degradation and increases GABA levels in the brain. CPP-115 hydrochloride does not bind to GABA transporters, does not displace GABA from GABA A / GABA B receptors, and does not act as an agonist/antagonist of GABA C receptors. CPP-115 hydrochloride reduces cocaine-induced dopamine release, blocks cocaine-induced conditioned place preference, and suppresses seizure activity in a rat model of infantile spasms. CPP-115 hydrochloride can be used in research related to infantile spasms and epilepsy.

Application

Products | Products > Disease Areas > Epilepsy | Products > Disease Areas > Muscle Relaxation and Spasm | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Muscle Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Aminotransferases (Transaminases) | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-W1025152
• CAS No.: 760947-97-5
• Molecular Formula: C7H10ClF2NO2
• Molecular Weight: 213.61
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source