CLK1/4-IN-2 is a selective CLK1/4 inhibitor, with an IC 50 of 7 nM against CLK1 and an IC 50 of 2.3 nM against CLK4 . CLK1/4-IN-2 induces protein depletion in cancer cells and exhibits anticancer activity. CLK1/4-IN-2 can be used in research related to breast cancer , monocytic leukemia, bladder cancer , mammary adenocarcinoma and hepatocellular carcinoma.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > HDAC
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