ID110460002

Overview

ID110460002 possesses both full agonist activity at the μ -opioid receptor ( OPRM ) and agonist activity at the δ -opioid receptor ( OPRD ). ID110460002 acts as a potent agonist for the G protein pathways of both receptors, but exhibits only very weak partial agonist activity towards the β-arrestin-2 pathway. The agonistic potency of ID110460002 at OPRM has extremely high intrinsic activity and is unaffected by reduced receptor expression levels, while its potency at OPRD depends on receptor expression levels. ID110460002 displays tissue- or organ-dependent properties, and serves as a critical compound for investigating pain mechanisms and analgesia.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor | Products > Signaling Pathways > Arrestin

Product Information

• Catalog No.: HY-W414109
• CAS No.: 1172882-21-1
• Molecular Formula: C20H25FN4O
• Molecular Weight: 356.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source