4-MeO-MiPT is a serotonin transporter ( SERT ) inhibitor and serotonin 2A receptor ( 5-HT 2A ) agonist with pIC 50 and IC 50 values of 57 nM and 0.43 nM for human SERT, and pEC 50 and EC 50 values of 23 nM and 2.3 nM for human 5-HT 2A , respectively. 4-MeO-MiPT blocks serotonin uptake via SERT, acts as an agonist at 5-HT 2A receptors, and exhibits agonist activity at 5-HT 1A , 5-HT 1D , 5-HT 2B , and 5-HT 2C receptors. 4-MeO-MiPT can be used for the research of depression.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Serotonin Transporter | Products > Signaling Pathways > 5-HT Receptor
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