m,p-Dimethyl PPE

Overview

m,p-Dimethyl PPE is a D4 dopamine receptor ligand. m,p-Dimethyl PPE promotes GDP/GTP exchange of the G protein α-subunit, dissociates the receptor-G protein complex, stabilizes the low-affinity receptor state, and inhibits adenylate cyclase activity. m,p-Dimethyl PPE inhibits Forskolin ( HY-15371 )-induced melatonin synthesis in retinal photoreceptor cells and reduces the efficacy of full agonists when used in combination. m,p-Dimethyl PPE can be used in studies related to attention-deficit hyperactivity disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > Adenylate Cyclase

Product Information

• Catalog No.: HY-W686762
• CAS No.: 219704-16-2
• Molecular Formula: C16H26ClN
• Molecular Weight: 267.84
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source