2-Propylpent-4-ynoic acid

Overview

2-Propylpent-4-ynoic acid (4-yn-VPA) is a HDAC inhibitor (with an IC 50 of 0.5 mM against human HDAC ). 2-Propylpent-4-ynoic acid also induces P-glycoprotein function, and exhibits teratogenicity, fetal growth inhibition and neurotoxicity. 2-Propylpent-4-ynoic acid shows significant stereospecific teratogenic effects, with the S-enantiomer being more teratogenic than the R-enantiomer and other analogs. The neurotoxicity of 2-Propylpent-4-ynoic acid is independent of its stereochemical structure. 2-Propylpent-4-ynoic acid has been used in studies related to the pathogenesis of colon cancer and neural tube defects such as exencephaly.

Application

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Product Information

• Catalog No.: HY-W787758
• CAS No.: 24102-11-2
• Molecular Formula: C8H12O2
• Molecular Weight: 140.18
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source