BAP2

Overview

BAP2 is an allosteric protein disulfide isomerase ( PDI ) inhibitor with a IC 50 of 0.85 μM. BAP2 binds to His256 in the b′ domain of PDI and exerts inhibitory effects through allosteric binding to the b′ domain. BAP2 upregulates GRP78 . BAP2 inhibits the growth of glioblastoma cells. BAP2 can be used in studies related to glioblastoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > CNS Neoplasm | Products > Disease Areas > Glioma | Products > Disease Areas > Glioblastoma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PDI

Product Information

• Catalog No.: HY-W851050A
• CAS No.: 2284589-16-6
• Molecular Formula: C16H11NO2
• Molecular Weight: 249.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source