Sodium metatungstate (Sodium polyoxotungstate) is a NTPDase inhibitor, with K i values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 ( CD39 ), NTPDase 3 and NTPDase 2 respectively. Sodium metatungstate has anti-inflammatory and anti-cancer effect. Sodium metatungstate inhibits ATP breakdown but also blocks central synaptic transmission.
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