(Rac)-AMG8379

Overview

(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide antagonist of NaV1.7, with IC 50 s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7, respectively .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-108425B
• CAS No.: 1641574-26-6
• Molecular Formula: C25H16ClF2N3O5S
• Molecular Weight: 543.93
• Purity: 99.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.82 mM); Clear solution
• Availability: In-stock

Source

Original product source