Cenicriviroc mesylate

Overview

Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | CCR

Product Information

• Catalog No.: B0084-286545
• CAS No.: 497223-28-6
• Molecular Formula: C42H56N4O7S2
• Molecular Weight: 793.051
• Purity: 99.04%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
• Solubility: In Vitro : DMSO : 100 mg/mL(126.10 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:5% DMSO >> 40%PEG300 >> 5%Tween-80 >> 50% saline Solubility: 2.5 mg/mL (3.15 mM); Clear solution; Need ultrasonic 2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.08 mg/mL (2.62 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.08 mg/mL (2.62 mM); Clear solution

Source

Original product source