BLZ945

Overview

BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC50 of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRb).

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | c-FMS

Product Information

• Catalog No.: B0084-463485
• CAS No.: 953769-46-5
• Molecular Formula: C20H22N4O3S
• Molecular Weight: 398.48
• Purity: >98%
• Storage: Store at -20°C
• Solubility: Soluble in DMSO, not in water

Source

Original product source