Epacadostat

Overview

Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | IDO

Product Information

• Catalog No.: B0084-465275
• CAS No.: 1204669-58-8
• Molecular Formula: C11H13BrFN7O4S
• Molecular Weight: 438.23
• Purity: ≥95%
• Storage: Store at -20°C
• Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

Source

Original product source