BI-847325

Overview

BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Aurora Kinase

Product Information

• Catalog No.: B0084-470824
• CAS No.: 1207293-36-4
• Molecular Formula: C29H28N4O2
• Molecular Weight: 464.56
• Purity: 98%
• Storage: 3 years -20°C powder; 6 months -80°C in solvent
• Solubility: DMSO: 19mg/mL warmed(40.89mM); Ethanol: 1mg/mL(2.15mM); Water: <1mg/mL(<1mM)

Source

Original product source