DM4

Overview

DM4 is an anti-tubulin agent that inhibits cell division. DM4 can be used to prepare antibody-drug conjugates. DM4 binds to tubulin at the maytansine-binding site, disrupting microtubule assembly/disassembly dynamics and inhibiting mitosis. Source summary: DM4, a maytansinoid ADC payload, inhibits tubulin assembly and is widely applied in cytotoxic ADCs for cancer therapy.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | Microtubule/Tubulin

Product Information

• Catalog No.: B0238-477049
• CAS No.: 796073-69-3
• Molecular Formula: C38H54ClN3O10S
• Molecular Weight: 780.37
• Purity: ≥95%
• Storage: Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
• Solubility: Soluble in DMSO

Source

Original product source