Irofulven

Overview

Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. Source summary: Irofulven is a DNA-alkylating ADC payload derived from mushroom toxin, used in antibody-drug conjugates for selective cytotoxic delivery.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | DNA Alkylator/Crosslinker

Product Information

• Catalog No.: B2693-059994
• CAS No.: 158440-71-2
• Molecular Formula: C15H18O3
• Molecular Weight: 246.12
• Purity: ≥95%
• Storage: Store at -20°C under inert atmosphere
• Solubility: Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly)

Source

Original product source