Mitoxantrone

Overview

Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Topoisomerase

Product Information

• Catalog No.: B2693-074515
• CAS No.: 65271-80-9
• Molecular Formula: C22H28N4O6
• Molecular Weight: 444.48
• Purity: >98%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
• Solubility: In vitro : 10 mM in DMSO

Source

Original product source