Tivozanib

Overview

Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis. Check for active clinical trials or closed clinical trials using this agent.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | VEGFR

Product Information

• Catalog No.: B2693-413727
• CAS No.: 475108-18-0
• Molecular Formula: C22H19ClN4O5
• Molecular Weight: 454.86
• Purity: ≥95%
• Storage: Store at 2-8 °C, sealed storage, away from moisture and light
• Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

Source

Original product source