Isorhynchophylline

Overview

Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and anticonvulsant activity of the Uncaira species plant extracts. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, the present results suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | SOD (Superoxide Dismutase)

Product Information

• Catalog No.: B2703-465032
• CAS No.: 6859-01-4
• Molecular Formula: C22H28N2O4
• Molecular Weight: 384.47
• Purity: >98%
• Storage: Store at -20°C
• Solubility: Soluble in Chloroform (Slightly), Ethanol (Slightly)

Source

Original product source