Isorhynchophylline

Isorhynchophylline
  • CAS No.:6859-01-4
  • Grade:>98%
  • Formula:C22H28N2O4
  • M.W.:384.47
  • Solvent:Soluble in Chloroform (Slightly), Ethanol (Slightly)

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and anticonvulsant activity of the Uncaira species plant extracts. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, the present results suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | SOD (Superoxide Dismutase)

Product Information

  • Catalog No.: B2703-465032
  • CAS No.: 6859-01-4
  • Molecular Formula: C22H28N2O4
  • Molecular Weight: 384.47
  • Purity: >98%
  • Storage: Store at -20°C
  • Solubility: Soluble in Chloroform (Slightly), Ethanol (Slightly)

Source

Original product source


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