4-IBP

Overview

4-IBP is a selective σ₁ receptor agonist with high affinity for the σ₁ receptor ( K i =1.7 nM) and moderate affinity for the σ₂ receptor ( K i = 25.2 nM). 4-IBP can make cancer cells more sensitive to the cytotoxic effects of pro-apoptotic and pro-autophagic compounds. 4-IBP significantly reduces the migration ability of a variety of cancer cells. 4-IBP is mainly used in glioblastoma, non-small cell lung cancer and prostate cancer research.

Application

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Product Information

• Catalog No.: HY-100155
• CAS No.: 155798-08-6
• Molecular Formula: C19H21IN2O
• Molecular Weight: 420.29
• Purity: 98.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.95 mM); Clear solution
• Availability: In-stock

Source

Original product source