(1R,3R)-RSL3

Overview

(1R,3R)-RSL3 is an isomer of RSL3 ( HY-100218A ). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) ( ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > Ferroptosis

Product Information

• Catalog No.: HY-100218C
• CAS No.: 1219810-15-7
• Molecular Formula: C23H21ClN2O5
• Molecular Weight: 440.88
• Purity: 99.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source