IQ-1S is a prospective inhibitor of NF-κB/activating protein 1 ( AP-1 ) activity with an IC 50 of 1.8 μM. IQ-1 has binding affinity (K d values) in the nanomolar range for all three JNK s with K d s of 87 nM, 360 nM, and 390 nM for JNK3 , JNK2 , and JNK1 , respectively.
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > JNK
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