SIS3 free base

Overview

SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1 . SIS3 free base does not affect the phosphorylation of Smad2 .

Application

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Product Information

• Catalog No.: HY-100444
• CAS No.: 521985-36-4
• Molecular Formula: C28H27N3O3
• Molecular Weight: 453.53
• Purity: 98.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.51 mM); Clear solution
• Availability: In-stock

Source

Original product source