CJ-17493 is a neurokinin-1 ( NK1 ) receptor antagonist, with a K i of 0.2 nM. CJ-17493 shows moderate affinity for the verapamil-binding site of L-type Ca 2+ channels ( IC 50 = 164 nM) and site 2 of sodium channels (IC 50 = 48 nM). CJ-17493 can be used for the study of neurological diseases.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neurokinin Receptor
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