BMS-986020 sodium

Overview

BMS-986020 (AM152) sodium is a high-affinity lysophosphatidic acid receptor 1 ( LPA1 ) antagonist. BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC 50 s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

Application

Products | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor

Product Information

• Catalog No.: HY-100619A
• CAS No.: 1380650-53-2
• Molecular Formula: C29H25N2NaO5
• Molecular Weight: 504.51
• Purity: 99.88%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 7.5 mg/mL (14.87 mM); Clear solution
• Availability: In-stock

Source

Original product source