L002

Overview

L002 is a potent, cell permeable, reversible and specific acetyltransferase p300 (KAT3B) inhibitor with an IC 50 of 1.98 μM. L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 activation. L002 has the potential for hypertension-induced cardiac hypertrophy and fibrogenesis treatment.

Application

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Product Information

• Catalog No.: HY-100671
• CAS No.: 321695-57-2
• Molecular Formula: C15H15NO5S
• Molecular Weight: 321.35
• Purity: 99.44%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (6.47 mM); Clear solution
• Availability: In-stock

Source

Original product source