(2R)-SR59230A is the isomer of SR59230A ( HY-100672 ), and can be used as an experimental control. SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC 50 s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively.
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