IWP-O1

Overview

IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC 50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Porcupine | Products > Signaling Pathways > Wnt

Product Information

• Catalog No.: HY-100853
• CAS No.: 2074607-48-8
• Molecular Formula: C26H20N6O
• Molecular Weight: 432.48
• Purity: 99.81%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (4.81 mM); Clear solution
• Availability: In-stock

Source

Original product source