ML364

Overview

ML364 is a selective ubiquitin specific peptidase 2 ( USP2 ) inhibitor ( IC 50 =1.1 μM) with anti-proliferative activity, which direct binds to USP2 ( K d =5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.

Application

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Product Information

• Catalog No.: HY-100900
• CAS No.: 1991986-30-1
• Molecular Formula: C24H18F3N3O3S2
• Molecular Weight: 517.54
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.83 mM); Clear solution
• Availability: In-stock

Source

Original product source