4-DAMP

Overview

4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors . 4-DAMP combined with 5-Fluorouracil (5-Fu) ( HY-90006 ) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC ( MUC5AC ), oligomeric mucus/gel-forming secretion.

Application

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Product Information

• Catalog No.: HY-100958
• CAS No.: 1952-15-4
• Molecular Formula: C21H26INO2
• Molecular Weight: 451.34
• Purity: 99.96%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 5 mg/mL (11.08 mM); Clear solution
• Availability: In-stock

Source

Original product source