Adenosine 5′-diphosphoribose (ADP ribose) is a nicotinamide adenine nucleotide (NAD + ) metabolite. Adenosine 5′-diphosphoribose is the most potent and primary intracellular Ca 2+ -permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose also can enhance autophagy .
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