FG 7142

Overview

FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor ( K i =91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit ( EC 50 = 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex.

Application

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Product Information

• Catalog No.: HY-100991
• CAS No.: 78538-74-6
• Molecular Formula: C13H11N3O
• Molecular Weight: 225.25
• Purity: 99.43%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (11.10 mM); Clear solution
• Availability: In-stock

Source

Original product source