MBM-17 is a potent NIMA-related kinase 2 ( Nek2 ) inhibitor with an IC 50 of 3 nM. It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis . MBM-55 shows antitumor activities, and no obvious toxicity to mice.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > NEKs | Products > Signaling Pathways > Apoptosis
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