BU224 hydrochloride

Overview

BU224 hydrochloride is a selective and high affinity imidazoline I 2 receptor ligand, with a K i of 2.1 nM. BU224 hydrochloride is sometimes used as an I 2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Aβ-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimer's disease research .

Application

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Product Information

• Catalog No.: HY-101170
• CAS No.: 205437-64-5
• Molecular Formula: C12H12ClN3
• Molecular Weight: 233.70
• Purity: 96.96%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.25 mg/mL (5.35 mM); Clear solution
• Availability: In-stock

Source

Original product source