CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available BCR-ABL , SRC and p38 kinase inhibitor with IC 50 values of 70, 90 and 62 nM against ABL1 , SRC and p38, respectively.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > Src | Products > Signaling Pathways > p38 MAPK
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