TPMPA

Overview

TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABA C receptor ( K B = 2.1 μM), but not to interact with GABA A ( K B = 320 μM) or GABA B receptors ( EC 50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-101359
• CAS No.: 182485-36-5
• Molecular Formula: C6H12NO2P
• Molecular Weight: 161.14
• Purity: 99.9%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source