AGN 192403 hydrochloride

Overview

AGN 192403 (BRD4780) hydrochloride is a potent and selective imidazoline-1 receptor antagonist with a K i value of 42 nM. AGN 192403 hydrochloride is also a TMED9 inhibitor. AGN 192403 hydrochloride shows protective effects on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes. AGN 192403 hydrochloride mitigates the proliferation and migration of differentiated glioma tumor cells. AGN 192403 hydrochloride can be used for glioma tumor and neurological diseases research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Glioma | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Imidazoline Receptor | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Lactate Dehydrogenase

Product Information

• Catalog No.: HY-101374A
• CAS No.: 1021868-90-5
• Molecular Formula: C10H20ClN
• Molecular Weight: 189.73
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (13.18 mM); Clear solution
• Availability: In-stock

Source

Original product source