Harmane-d 1

Harmane-d 1
  • CAS No.:3013688-52-0
  • Grade:98.01%
  • Formula:C12H9DN2
  • M.W.:183.23

Overview

Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor ( IC 50 =30 nM) over α2-adrenoceptor ( IC 50 =18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) ( IC 50 s=0.5 and 5 μM for human MAO A/B, respectively).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Imidazoline Receptor | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Adrenergic Receptor

Product Information

  • Catalog No.: HY-101392S
  • CAS No.: 3013688-52-0
  • Molecular Formula: C12H9DN2
  • Molecular Weight: 183.23
  • Purity: 98.01%
  • Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
  • Availability: In-stock

Source

Original product source


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