Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor ( IC 50 =30 nM) over α2-adrenoceptor ( IC 50 =18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) ( IC 50 s=0.5 and 5 μM for human MAO A/B, respectively).
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Imidazoline Receptor | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Adrenergic Receptor
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.