Fenobam hydrate

Overview

Fenobam hydrate is a selective and orally active mGluR5 antagonist ( IC 50 =84 nM) that can penetrate the blood-brain barrier. Fenobam hydrate shows the K d values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate has anxiolytic activity, inhibits self-administration behavior in rat, and induces apoptosis in cancer cells. Fenobam hydrate can be used for research on neurological diseases, cancer and drug addiction.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Signaling Pathways > mGluR | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-101478A
• CAS No.: 63540-28-3
• Molecular Formula: C11H13ClN4O3
• Molecular Weight: 284.70
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source