AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC 50 of 6.3 μM in FRET assay and a K d of 0.98 μM in surface plasmon resonance (SPR) assay.
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