Alvameline (Lu 25-109) maleate is a partial agonist of M1 and an antagonist of M2/M3 . Alvameline maleate competitively antagonizes contractions induced by ammonium chloride ( HY-Y1269 ) and electrical field stimulation in human detrusor muscle, indicating its potential application in regulating bladder function. Additionally, alvameline maleate can improve cognitive function following traumatic brain injury in rats.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR
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