Rocastine (AHR-11325 ) is an orally active H 1 -histamine receptor inhibitor that selectively binds to and functionally inhibits H1-histamine receptors. Rocastine protects guinea pigs from the lethal effect induced by Histamine ( HY-B1204 ), prevents histamine-induced collapse, and protects guinea pigs from the falling reaction induced by nebulized antigens. Rocastine can be used in the research of allergic diseases.
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