NOD1/2 antagonist-2

Overview

NOD1/2 antagonist-2 (Compound 26BH) is a dual NOD1/NOD2 antagonist ( IC 50 s: 2.36 μM and 4.16 μM for NOD1 and NOD2 , respectively). NOD1/2 antagonist-2 inhibits both NF-κB and MAPK inflammatory signaling, thereby sensitizing Paclitaxel ( HY-B0015 ) to suppress Lewis lung carcinoma growth.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-101927
• CAS No.: 2101736-25-6
• Molecular Formula: C32H37N5O6
• Molecular Weight: 587.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source