hVEGF-IN-1

Overview

hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a K d of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression.

Application

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Product Information

• Catalog No.: HY-101931
• CAS No.: 1637443-98-1
• Molecular Formula: C34H43N7O2
• Molecular Weight: 581.75
• Purity: 99.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution
• Availability: In-stock

Source

Original product source