LY 345899

Overview

LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase ( MTHFD1 ; DC301 ) and MTHFD2 inbhibitor with IC 50 values of 96 nM and 663 nM, respectively and a K i of 18 nM for MTHFD1 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Methylenetetrahydrofolate Dehydrogenase (MTHFD)

Product Information

• Catalog No.: HY-101943
• CAS No.: 10538-99-5
• Molecular Formula: C20H21N7O7
• Molecular Weight: 471.42
• Purity: 98.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.30 mM); Clear solution
• Availability: In-stock

Source

Original product source