(3aR)-Selitrectinib ((3aR)-LOXO-195) is an isform of Selitrectinib ( HY-101977 ), which is a next-generation TRK kinase inhibitor, with IC 50 s of 0.6 nM and <2.5 nM for TRKA and TRKC , respectively.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Trk Receptor
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